Together with Chico and Trampi, Zagor helps Pickens free his wife, and eventually clashes with the kidnappers, where he meets the titular Mr. Smith, a strange man who is in fact the real reason for all this complication.
The mad genius Hellingen comes up with the idea of putting the giant Titan back on its feet for the second time, with the help of Zagor. He sends the Ghost with an axe to the bottom of Lake Erie. The plan is good, but...
Zagor against Governor Sombra, the scientist Coronado and their mercenaries who kidnapped a Hopi shaman and his daughter to take them to the treasure hidden in the mythical Seven Cities of Cibola...